Taurine danger with other drugs8/29/2023 Vitamin C appears to increase the effectiveness of chemotherapy in animals and with human breast cancer cells in test tube research. However, most scientific research does not support this supposition.Ī modified form of vitamin A has been reported to work synergistically with chemotherapy in test tube research. Limited test tube research occasionally does support the idea that an antioxidant can interfere with oxidative damage to cancer cells. As a result, some oncologists recommend that patients avoid supplementing antioxidants if they are undergoing chemotherapy. In a double-blind study, supplementation with 18 grams of glutamine per day for 15 days, starting five days before the beginning of 5-FU therapy, significantly reduced the severity of drug-induced intestinal toxicity.Ĭhemotherapy can injure cancer cells by creating oxidative damage. Intravenous use of glutamine in people undergoing bone marrow transplants, a procedure sometimes used to allow very high amounts of chemotherapy to be used, has led to reduced hospital stays, leading to a savings of over $21,000 for each patient given glutamine. However, other studies using higher amounts or intravenous glutamine have not reported this effect. One double-blind trial suggested that 6 grams of glutamine taken three times per day can decrease diarrhea caused by chemotherapy. In another study, patients receiving high-dose paclitaxel and melphalan had significantly fewer episodes of oral ulcers and bleeding when they took 6 grams of glutamine four times daily along with the chemotherapy. These excellent results have been duplicated in some, but not all double-blind research. Thirteen of fourteen people in the study had fewer days with mouth sores as a result. In one trial, people were given 4 grams of glutamine in an oral rinse, which was swished around the mouth and then swallowed twice per day. Glutamine has successfully reduced chemotherapy-induced mouth sores. In fact, animal studies show that glutamine may actually decrease tumor growth while increasing susceptibility of cancer cells to radiation and chemotherapy, though such effects have not yet been studied in humans. Though cancer cells use glutamine as a fuel source, studies in humans have not found that glutamine stimulates growth of cancers in people taking chemotherapy.
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